Etiology and Clinical profile of Pleural Effusion in a Teaching Hospital of South India : A Descriptive Study

Manu, Mohan K (2012) Etiology and Clinical profile of Pleural Effusion in a Teaching Hospital of South India : A Descriptive Study. Pulmon, 14 (3). pp. 89-96.

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Background & objectives: Etiological diagnosis of Pleural effusion (PE) is really challenging to physician. Knowledge of common etiologies of pleural effusion helps us in planning the approach when such a case is encountered. The study was an attempt to identify the common etiologies causing PE in a teaching institute and their clinical profile. Materials and Methods: A prospective evaluation of 100 consecutive cases of PE. Detailed history and physical examination, thoracocentesis and pleural fluid analysis were done in all cases and closed pleural biopsy using cope needle, ultrasound examination and computerized tomography in indicated cases.Results : PE occurred more among males (68%) and in the age group between 46 to 60 years (33%). Majority of the cases (95%) were having exudative effusion. Tuberculosis was the commonest cause of exudative effusion (41%) followed by malignancy (38%). Majority of tuberculous PE (63%) was right sided whereas malignant effusion was left sided (57%). The Mantoux test, pleural fluid protein, pleural fluid ADA and age of patients had statistically significant correlation when PE due to tuberculosis and malignancy were compared.Conclusions: Tuberculosis and malignancy are the two major causes for PE in the hospital. Tuberculous PE predominates slightly than malignant effusion. Tuberculous PE occurred in younger age group. Pleural biopsy should be done in patients with negative pleural fluid cytology. Thoracoscopy should be done if all the other investigative modalities fail to yield a confirmatory result. Knowledge of etiological pattern helps to plan relevant investigations in patients with PE and reduces the delay in diagnosis.

Item Type: Article
Uncontrolled Keywords: Pleural effusion; Tuberculosis; Malignancy; Adenosine deaminase; Needle biopsy; Etiology
Subjects: Medicine > KMC Manipal > Pulmonary Medicine
Depositing User: KMC Manipal
Date Deposited: 22 Sep 2014 04:32
Last Modified: 22 Sep 2014 04:32

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