MU Digital Repository
Logo

Impaired heart response to deep breathing in diabetic cardiac autonomic neuropathy: Importance of age- related normal range

*, Subbalakshmi NK and Adhikari, Prabha (2014) Impaired heart response to deep breathing in diabetic cardiac autonomic neuropathy: Importance of age- related normal range. International Journal of Biomedical And Advance Research, 05 (09). pp. 429-431. ISSN 2229-3809

[img] PDF
article nks.pdf - Published Version
Restricted to Registered users only

Download (275kB) | Request a copy

Abstract

Introduction: Ewing’s battery of cardiac autonomic function tests provides a single value ignoring the decline in autonomic function with ageing. Objective: To derive age related normal range of heart rate response to deep breathing at six respiratory cycles per minute (HRV) from healthy subjects and estimate the prevalence of cardiac autonomic dysfunction in diabetes. Materials and Methods: HRV was measured in 207 subjects with type 2 diabetes mellitus and 141 healthy subjects matched for age and sex of diabetics. Abnormal scores had been defined as those more than 2 standard deviation below the mean value in controls. Results: Diabetics had lower HRV compared to controls in above the ≤ 40 year’s age groups (p < 0.0001). Abnormal HRV expressed in beats per minute for different class intervals of age was: ≥ 40 years: < 17; 41-50 years :< 13; 51-60 years: < 11; ≥ 61 years :< 7.Abnormal HRV was observed in 11.59% of diabetics. Conclusion: Single value generates falls negative results among younger and falls positive results among older age groups. Thus age related normal range of HRV is appreciated in defining cardiac parasympathetic dysfunction in diabetics.

Item Type: Article
Uncontrolled Keywords: ageing, normal range of HRV, parasympathetic dysfunction
Subjects: Medicine > KMC Mangalore > Physiology
Medicine > KMC Mangalore > Medicine
Depositing User: KMCMLR User
Date Deposited: 06 Oct 2014 11:47
Last Modified: 06 Oct 2014 11:47
URI: http://eprints.manipal.edu/id/eprint/140778

Actions (login required)

View Item View Item