Prevalence of Osteoporosis among Diabetics - A Prospective Study

Patil, N and Mathew, R and Shenoy, S and Bhandarkar, Anoosha P (2014) Prevalence of Osteoporosis among Diabetics - A Prospective Study. International Journal of Pharmaceutical Research and Bio-Science, 3 (5). pp. 354-361. ISSN 2277-8713

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Abstract

Summary: Diabetes mellitus patients were assessed based on the bone scan values and thereby it was found out that there is more risk of osteoporosis in type 1 diabetes mellitus patients in comparison to type 2 patients. Introduction: Amidst controversies, the degree of bone loss differs in type 1 DM and type 2 DM and hence it is indeed a debatable topic. The present study is aimed so as to understand the prevalence of osteoporosis among type 1 DM and type 2 DM patients and to analyze as to which type of diabetic patients are more prone to osteoporosis. Methods: A prospective, comparative study was conducted in 200 patients suffering from type 1 or 2 diabetes mellitus of either sex. Patients with fasting blood sugar greater than 126mg/dl or random blood sugar greater than 200mg/dl were diagnosed to have diabetes mellitus and was included in the study. Blood tests showing auto antibodies and presence of ketone bodies in urine were considered as type 1 diabetics and its absence were considered as type 2 diabetics. . Bone mineral density (BMD) was obtained via dual x-ray absorptiometry (DXA). Results: Among the total number of 200 diabetic patients, males were 27.5% and females were 72.5%.62 patients suffered from type 1 diabetes mellitus, in which males were 24.19% and females were 75.8%.Patients with type 2 diabetes mellitus was 138, in which 28.98% were males and 71.01% were females. Based on bone scan readings, patient with a T score < -2.5 were considered osteoporotic and thereby its prevalence among different diabetic patients were assessed. There was a significant difference in the prevalence of osteoporosis among the two types of diabetic patients (p<0.001).Among the type 1 diabetics, 54.83% patients had osteoporosis and among the type 2 diabetics, 19.56% patients had osteoporosis. Conclusions: Both the types of diabetic patients showed prevalence of osteoporosis however patients with type 1 diabetes mellitus were comparatively more prone to osteoporosis than type II diabetic patients.

Item Type: Article
Uncontrolled Keywords: Osteoporosis; Type 1 DM; Type 2 DM; Bone mineral densi
Subjects: Medicine > MMMC Manipal > Pharmacology
Medicine > KMC Manipal > Pharmacology
Depositing User: KMC Manipal
Date Deposited: 11 Nov 2014 10:22
Last Modified: 10 Jan 2015 04:52
URI: http://eprints.manipal.edu/id/eprint/141038

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