Synthesis, characterization and biological studies of 2,5-substituted 1,3,4- thiadiazole carrying 1,2,3-triazole core

Ballal, Mamatha and Shetty, Vignesh (2014) Synthesis, characterization and biological studies of 2,5-substituted 1,3,4- thiadiazole carrying 1,2,3-triazole core. Journal of Chemical and Pharmaceutical Research, 6 (11). pp. 374-380. ISSN 0975-7384

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Abstract

A new series of amides (7a-m) from 2,5-substituted-1,3,4-thiadiazoles carrying 1,2,3-triazoles have been synthesized starting from 4-nitroaniline. The structures of these newly synthesized compounds were elucidated by elemental analysis, 1H NMR and mass spectral data. Also these compounds were evaluated for their antibacterial activity against bacteria Pseudomonas, Staphylcoccus aureus, Enterococcus, Eschericia coli and antifungal activity against Candida albicans, and antioxidant activity by DPPH radical scavenging assay method.

Item Type: Article
Uncontrolled Keywords: Thiadiazole; 1,2,3,-triazole; antibacterial; antioxidant activity.
Subjects: Medicine > KMC Manipal > Microbiology
Depositing User: KMC Manipal
Date Deposited: 04 Dec 2014 04:31
Last Modified: 04 Dec 2014 04:31
URI: http://eprints.manipal.edu/id/eprint/141194

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