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Comparision of Mifepristone and Misoprostol in the Induction of Labor At Term

*, Raksha M. and Rao, Arun A and *, Shameem VPA (2014) Comparision of Mifepristone and Misoprostol in the Induction of Labor At Term. Indian Journal of Research, 3 (11). pp. 117-119. ISSN 2250-1991

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Abstract

Aim: To assess the ability of mifepristone and misoprostol individually in priming the cervix. When mifepristone alone is insufficient, to determine if vaginal misoprostol used sequentially, is effective in inducing labor. Methods: prospective randomized comparative study conducted in LadyGoschen Hospital, Mangalore. Inclusion criteria: singleton term pregnancy and Bishop’s score <6. Exclusion criteria:Parity >5, scarred uterus, cephalopelvic disproportion, antepartum hemorrhage, oligohydramnios. Statistical analysis:was performed using the χ2 test, p-value of <0.05 was considered significant. Results: The study demonstrated significant efficacy of mifepristone for cervical ripening and induction of spontaneous labor after drug administration. In the present study 66% of women entered labor spontaneously or had a sufficiently ripened cervix within 48hrs of intake of mifepristone, but there was no difference in time between misoprostol administration and delivery interval between the groups. There were less number of LSCS in the mifepristone group but the difference was not statistically significant. Maternal and neonatal outcomes were comparable in both groups.

Item Type: Article
Uncontrolled Keywords: Misoprostol , Induction, Mifepristone
Subjects: Medicine > KMC Mangalore > Obstetrics & Gynaecology
Depositing User: KMCMLR User
Date Deposited: 04 Dec 2014 09:56
Last Modified: 04 Dec 2014 09:56
URI: http://eprints.manipal.edu/id/eprint/141198

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