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Retrospective surveillance for intussusception in children aged lessthan five years at two tertiary care centers in India

Kamath, V and Shetty, Ranjitha S and Kumar, V Retrospective surveillance for intussusception in children aged lessthan five years at two tertiary care centers in India. Vaccine, 32 (1). A95-A98. ISSN 0264-410X

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Abstract

Background: A rotavirus vaccine could soon become part of India’s national immunization program.However the occurrence of intussusception due to rotavirus vaccine is a potential safety concern. Thissurveillance aimed at the collection of baseline data on childhood intussusception which would facilitatethe monitoring of intussusception cases after the introduction of rotavirus vaccines. Methods: We retrospectively reviewed medical records of confirmed intussusception cases in childrenunder the age of five, treated during 2007–2012 at two tertiary care hospitals attached to medical schoolsin India. Demographic, clinical, diagnostic and treatment practices data were obtained from hospitalrecords. Results: Over a five to six year observation period, we identified 187 confirmed cases of intussusception,of which 75% were males. The median age of intussusception was 8 months, and we observed a possibletrend in the distribution of cases with the highest number of cases being reported in the month of Apriland lowest in the month of October. The most common diagnostic methods used were ultrasonographyand abdominal radiography with most cases being treated surgically (71%). The median length of hospitalstay was 8 days (range 1–40) and mean was 10.2 days. Records of any fatality due to intussusception werenot found during the review of the records. Conclusions: This analysis provides an estimate of the baseline data of childhood intussusception priorto the introduction of the rotavirus vaccination as a part of routine immunization in India. A prospec-tive surveillance system using a standardized case definition is needed in order to better examine theincidence of intussusception in developing countries.

Item Type: Article
Uncontrolled Keywords: Intussusception ; IndiaUnder-five ; Rotavirus.
Subjects: Medicine > KMC Manipal > Community Medicine
Depositing User: KMC Manipal
Date Deposited: 15 Jan 2015 04:55
Last Modified: 15 Jan 2015 04:55
URI: http://eprints.manipal.edu/id/eprint/141601

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