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Protective Role of Aqueous Leaf Extract of Moringa oleiferaon Blood Parameters in Cadmium Exposed Adult Wistar Albino Rats

*, Vinodini N.A and Chatterjee, Pratik Kumar and Chatterjee, Poulomi and Chakraborti, Shrijeet and *, Nayanatara AK and Bhat , Ramesh M and *, Rashmi KS and *, Suman VB and Shetty, Sneha B and Pai, Sheila R (2015) Protective Role of Aqueous Leaf Extract of Moringa oleiferaon Blood Parameters in Cadmium Exposed Adult Wistar Albino Rats. International Journal of Current Research & Academic Review , 3 (1). pp. 192-199.

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Abstract

Cadmium is one of the toxic, hazardous metals widely dispersed in the environment in high levels. Studies have shown that excessive exposure of this biological hazard can even cause death. It is well known that the most important tissue in our body in which metabolic changes are reproduced is the blood. The present study was conducted to evaluate the role of Moringa oleifera leaf extract on haematological parameters in cadmium exposed rats. Twenty-four adult male Wistar Albino rats, weighing between (180-200) g were broadly divided into four groups, each had six animals, with group I being the control. Pre-treatment with Moringa leaf extract, 100 mg/kg/bw, prior to the administration of cadmium showed a significant increase(p< 0.0001) in the haematological parameters, like red blood cell (RBC) count, haemoglobin (Hb) concentration, packed cell volume (PCV), mean corpuscular haemoglobin (MCH) & a decrease in mean corpuscular volume (MCV) as compared to the cadmium treated group. Therefore, our results suggest that aqueous leaf extract of Moringa oleifera has a positive effect on cadmium induced anaemia & other manifestations induced by this biological toxicant.

Item Type: Article
Uncontrolled Keywords: Cadmium, Moringa oliefera, haematological parameters, anaemia
Subjects: Medicine > KMC Mangalore > Pathology
Medicine > KMC Mangalore > Physiology
Depositing User: KMCMLR User
Date Deposited: 22 Jan 2015 06:47
Last Modified: 22 Jan 2015 06:47
URI: http://eprints.manipal.edu/id/eprint/141694

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