Comparison of RR100, R10 and morphologic guided list criteria in rescreening of 4000 cervical smears – an experience in a tertiary care hospital

Rao, Anuradha CK and Nayal, Bhavna and Patil, Raveendra G (2015) Comparison of RR100, R10 and morphologic guided list criteria in rescreening of 4000 cervical smears – an experience in a tertiary care hospital. International Journal of Scientific and Research Publications, 5 (1). pp. 1-6. ISSN 2250-3153

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Abstract

One of the most common malignancies to afflict women, cervical cancers have a high worldwide incidence. Papanicolau (Pap) test is the screening tool, ustilised widely for early detection of cervical neoplasias. However, a high load of Pap smears has resulted in errors associated with this test. Rescreening methods serve to monitor this primary cervical screening programme. This study was carried out to detect epithelial abnormalities which were otherwise missed on primary screening, using different rescreening methods and to identify the cause for such error. Materials and methods: A retrospective study utilizing 4000 consecutive Pap smears reported in a tertiary care hospital was done. Three thousand seven hundred forty five adequate smears diagnosed as negative for intraepithelial lesion (NILM) and atypical squamous cells of undetermined significance (ASCUS) were included in the study. These smears were rescreened using 100% rapid review, 10% random review and morphologic guided list criteria (MGLC) methods. The discrepancy between the results of original cytological diagnosis and the three rescreening methods were then analysed. Results: In the original Pap test, epithelial abnormalities accounted for only 0.85% of the total smears studied. Using RR100 and R10 methods epithelial abnormalities detected were 1.77% and 0.70% among NILM and ASCUS. No epithelial abnormalities were seen on MGLC rescreening test. Conclusion: Rescreening methods are essential to detect screening errors, as these can have far reaching consequences in prevention of advances in cervical dysplasia. Of the various methods, 100%RR is the best available technique.

Item Type: Article
Uncontrolled Keywords: Rescreening; rapid review; random review; morphologic guided list criteria; Papanicolau test.
Subjects: Medicine > KMC Manipal > Pathology
Depositing User: KMC Manipal
Date Deposited: 28 Jan 2015 09:29
Last Modified: 07 Nov 2016 09:07
URI: http://eprints.manipal.edu/id/eprint/141738

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