Metastatic rhabdoid meningioma of the parotid – Mimicking primarysalivary gland neoplasm

Nair, Rajesh P and Vinod, * and Sarma, Yashdeep and Nayal, Bhavna and Kaur, Sumeet Dil and Tripathi, Pradeep Kumar (2015) Metastatic rhabdoid meningioma of the parotid – Mimicking primarysalivary gland neoplasm. International Journal of Surgery Case Reports, 6. pp. 104-106. ISSN 2210-2612

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Introduction: Tumors involving the parotid are predominantly primary with metastatic lesions forminga miniscule population. Meningioma metastasizing to the parotid is extremely rare and hence can oftenbe mistaken for the more common primary salivary gland neoplasms. Presentation of Case : A 59-year-old male presented with a swelling in the left parotid region. Fine nee-dle aspiration cytology was suggestive of myoepithelial predominant pleomorphic adenoma. A superficialparotidectomy performed revealed a tumor composed of rhabdoid cells with abundant finely granulareosinophilic cytoplasm raising a possibility of myoepithelioma. Immunohistochemistry for myoepithe-lial markers was negative. A critical review elicited a history of surgical excision of a recurrent rhabdoidmeningioma twice. A possibility of metastasis was considered and a second panel of immunomarkersdemonstrated vimentin and epithelial membrane antigen positivity. Neuroimaging studies demonstrateda space occupying lesion in the frontal lobe suggestive of a recurrent/residual tumor. In view of the his-tory, neuroradiology, histopathology and immunohistochemistry, a final diagnosis of metastatic rhabdoidmeningioma to the parotid was rendered. Discussion : Morphologically, metastatic rhabdoid meningioma may mimic a primary or metastatic car-cinoma, melanoma and sarcoma. Accurate diagnosis can be made by careful clinical evaluation andhistopathological examination of the tumor. These tumors are composed of rhabdomyoblast like cellswith abundant eosinophilic cytoplasm. The present case demonstrated characteristic histopathologicalfeatures confirmed by immunohistochemistry. Conclusion: Rhabdoid meningioma is an aggressive tumor with a high propensity to recur and metasta-size. The present case highlights the importance of clinical, radiological and histopathological correlationto accurately diagnose these rare entities.

Item Type: Article
Uncontrolled Keywords: Rhabdoid meningioma ; Parotid metastasisa.
Subjects: Medicine > KMC Manipal > Neuro Surgery
Medicine > KMC Manipal > Pathology
Medicine > KMC Manipal > Surgery
Depositing User: KMC Manipal
Date Deposited: 28 Jan 2015 09:57
Last Modified: 28 Jan 2015 09:57

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