The interaction surface of a bacterial transcription elongation factor required for complex formation with an antiterminator during transcription antitermination

Mishra, Saurabh (2013) The interaction surface of a bacterial transcription elongation factor required for complex formation with an antiterminator during transcription antitermination. The Journal of Biological Chemistry, 288 (39). pp. 28089-28103.

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Abstract

Background: The mode of interaction between the transcription factor, NusA, and the antiterminator, N, is unknown. Results: When bound to the transcription elongation complex (EC), NusA-NTD interacts with N. Conclusion: The EC-induced away-movement of NusA-C-terminal domain changed the interaction surface of NusA for N. Significance: N-NusA interaction converts NusA into an antiterminator by influencing the NusA-RNA polymerase interaction.

Item Type: Article
Subjects: Research > Research Center - Health Sciences
Depositing User: KMC Manipal
Date Deposited: 18 Feb 2015 06:21
Last Modified: 18 Feb 2015 06:21
URI: http://eprints.manipal.edu/id/eprint/141967

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