MRSA Prevalence and Antimicrobial Susceptibility Pattern of Orthopedic Surgery Patients of a Tertiary Care Hospital, South India

Latha, T and Bhat, AK and Hande, HM and Mukhopadyay, C and George, A and Devi, Elsa Sanatombi (2014) MRSA Prevalence and Antimicrobial Susceptibility Pattern of Orthopedic Surgery Patients of a Tertiary Care Hospital, South India. Asian Journal of Medical and Clinical Sciences, 3 (1). pp. 1-4.

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Abstract

Background and objective: Methicillin Resistant Staphylococcus Aureus (MRSA) is found globally. Though it is present as normal flora in many healthy individual, it has the capacity to cause mild to severe infection. The wound infected with MRSAtakes a longer time for healing and increases the mortality and health care cost. This study was conducted to find the prevalence of MRSAinfection and antimicrobial susceptibility pattern among Orthopedic surgery patients at a tertiary care hospital, Karnataka, South India. Methods: Medical records of all major Orthopedic surgery patients were reviewed retrospectively for 12 months from June 2011 to May 2012 for culture and sensitivity pattern. MRSA was detected from isolated staphylococcus aureus strains and the antimicrobial susceptibility pattern was identified through conventional method. Results: A total of 201 (57.26%) wound swabs documented to have MRSA strains from 351 S. Aureus isolates. Of the 201MRSA infected wound swabs, 92% were male with the mean age of 40.19 (SD 7.35) years. All (100 %) isolates of MRSA were resistant to Ampicillin, Ceftazidime, Cefotaxime and Cefuroxime while Chloramphenicol, Vancomycin, Linezolid, Rifampicin, and Teicoplanin were found to be sensitive with all (100%) strains of MRSA. Conclusions: The present study shows a high prevalence of MRSAinfection in a selected cohort of patients. Vancomycin, Linezolid, Rifampicin, and Teicoplanin are the drugs of choice to treat MRSAinfection as these were found to be absolutely sensitive to MRSA. Since this superbug infection can lead to increased morbidity and mortality in these patients, severe measures are needed to reduce the infection rate.

Item Type: Article
Uncontrolled Keywords: Methicillin Resistant Staphylococcus Aureus (MRSA); Orthopedic surgery; antibiotic sensitivity and resistance; infection.
Subjects: Medicine > KMC Manipal > Medicine
Medicine > KMC Manipal > Microbiology
Nursing > MCON Manipal > Medical Surgical
Medicine > KMC Manipal > Orthopaedics
Depositing User: KMC Manipal
Date Deposited: 30 Mar 2015 09:14
Last Modified: 30 Mar 2015 09:14
URI: http://eprints.manipal.edu/id/eprint/142291

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