Robust Controller for Blood Glucose Regulation in Type I Diabetics

Kamath, Surekha and George, V I and Vidyasagar, Sudha (2007) Robust Controller for Blood Glucose Regulation in Type I Diabetics. In: Proceedings of the national conference on Biomedical Engineering, October 5-6 2007.

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Insulin injection therapy is widely practiced for the maintenance of blood glucose levels within the normoglycemic range (70-100mg/dL) for type I diabetes. A robust H infinity controller was designed to deliver insulin via a mechanical pump in type I diabetic patients, For the design of H infinity controller a linear diabetic patient model is necessary . Hence the nonlinear diabetic patient model was linearized around euglycemic condition. Uncertainty in the nonlinear model was characterized by up to ±40% variation in eight physiological parameters. A sensitivity analysis identified the three parameter set having the most significant effect on glucose and insulin over the frquency range of interest [0.02,0.2]. controller performance can be assessed in terms of ability to track a normoglycemic set point (81.1mg/dL) in response to a 50g meal disturbance.

Item Type: Conference or Workshop Item (Paper)
Uncontrolled Keywords: Diabetes control, Model based control, Robust H infinity control.
Subjects: Engineering > MIT Manipal > Instrumentation and Control
Medicine > KMC Manipal > Medicine
Depositing User: MIT Library
Date Deposited: 27 Apr 2015 06:15
Last Modified: 27 Apr 2015 06:15

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