Recurrent metastatic mixed germ cell tumor of central nervous system with additional seminomatous component

Chakraborti, Shrijeet and Kini, Hema and Rai, Santosh and *, Ashvini Kumar (2015) Recurrent metastatic mixed germ cell tumor of central nervous system with additional seminomatous component. Medical Journal of Dr. D.Y. Patil University, 8 (3). pp. 407-410. ISSN 0975-2870

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Abstract

Mixed germ cell tumors (GCTs) are aggressive tumors owing to poor response to therapy, frequent recurrence and metastasis. We present here a case of 29-year-old male with recurrent metastatic mixed GCT in the left parietal lobe, with right testicular primary. Interestingly, the recurrent tumor exhibited a seminomatous component, in addition to yolk sac tumor and embryonal carcinoma. The patient was treated with surgery, cranial radiotherapy and cisplatin-based chemotherapy. The metastatic intracranial tumor recurred twice and the patient died 18 months after the first appearance of central nervous system metastasis.

Item Type: Article
Uncontrolled Keywords: Cisplatin, embryonal carcinoma, metastasis, seminoma, yolk sac tumor, α-fetoprotein
Subjects: Medicine > KMC Mangalore > Pathology
Medicine > KMC Mangalore > Radio Diagnosis and Imaging
Depositing User: KMCMLR User
Date Deposited: 18 May 2015 06:24
Last Modified: 18 May 2015 06:24
URI: http://eprints.manipal.edu/id/eprint/142663

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