Anti-tubercular Activity of Synthesized Novel 2,5-disubstituted-1,3,4-oxadiazole Derivatives

Ega, D and Attari, Z and Mudgal, Jayesh and Bairy, Laxminarayana K and Vishnuprasad, S and Nampurath, Gopalan Kutty (2015) Anti-tubercular Activity of Synthesized Novel 2,5-disubstituted-1,3,4-oxadiazole Derivatives. Indian Drugs, 52 (2). pp. 40-44.

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Abstract

A few novel 2,5-disubstituted-1,3,4-oxadiazole derivatives were synthesized and evaluated for antitubercular activity. The anti-tubercular activity was carried out as per the Rist and Grosset proportion method. Among the eight derivatives, the compounds substituted at ortho-position of the aromatic ring showed anti-tubercular activity comparable with the standard, isoniazid.

Item Type: Article
Uncontrolled Keywords: Trberculosis;2,5-disubsstituted-1,3.4-oxadiazole derivatives; Anti-tubercular activity
Subjects: Pharmacy > MCOPS Manipal > Pharmacology
Depositing User: KMC Manipal
Date Deposited: 20 May 2015 03:46
Last Modified: 20 May 2015 03:46
URI: http://eprints.manipal.edu/id/eprint/142687

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