Rickettsial diseases in children

Shenoy, Suchitra M and Baliga, Shantharam B and *, Ashok J (2015) Rickettsial diseases in children. Journal of International Medicine and Dentistry, 2 (1). pp. 63-73. ISSN 2350-045X

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Abstract

In a tropical country like India, fevers are caused by different etiological agents. Rickettsial infections, which have a global distribution is one of the differential diagnosis in such cases and are reported from almost all parts of India. Rickettsial diseases widely vary in severity from self-limited mild illnesses to fulminating life-threatening infections. They are obligate intracellular gramnegative coccobacillary forms that multiply within eukaryotic cells which makes it difficult to culture them on artificial culture medium. With globalization there is rapid spread of disease across the continents and therefore, skills for diagnosis and management of the disease attains global importance. Rickettsial diseases can be clinically classified as Spotted Fever group, typhus group, distinctive clinical rickettsiae and emerging rickettsiae. The clinical course will have incubation period, stage non-specific clinical signs and symptoms followed by typical/classical features depending on the type of rickettsiae infecting a person. However the clinical manifestation varies from one geographical area to another area for same species. The rickettsial diseases once thought to have been eradicated from India are re-emerging in many parts of our country. Their presence has recently been documented in at least eleven states of our country. Greater clinical awareness, a higher index of suspicion, better use of available diagnostic tools would increase the frequency with which rickettsial diseases are diagnosed.

Item Type: Article
Uncontrolled Keywords: Rickettsial infections, typhus fevers, Weil Felix test, doxycycline
Subjects: Medicine > KMC Mangalore > Microbiology
Medicine > KMC Mangalore > Paediatrics
Depositing User: KMCMLR User
Date Deposited: 30 May 2015 06:32
Last Modified: 30 May 2015 06:32
URI: http://eprints.manipal.edu/id/eprint/142857

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