Serous atrophy of the marrow in anorexia nervosa – A case report

Chari, Brahmaiah KR and Manohar, Chethan and Kaur, Somal Puneet and Belurkar, Sushma V (2014) Serous atrophy of the marrow in anorexia nervosa – A case report. International Journal of Medical Science and Clinical Inventions, 1 (9). pp. 489-492. ISSN 2348-991X

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Anorexia nervosa is a psychiatric disorder characterized by a purposeful dietery restrictionand altered alimentary habits,with very few cases having been reported from India. Hematologic manifestations include cytopenias.Bone marrow aspirations usually yield a dry tap probably due to serous degeneration and biopsy usually reveals alterations in bone marrow adipocytes with deposition of pink homogeneous material. Serous atrophy of bone marrow is a rare disorder characterized by fat cell atrophy, loss of hematopoietic tissueand deposition of extracellular matrix by mucopolysaccaharides. It has been described ina variety of chronic diseases like cancer-related cachexia, anorexia nervosa due to starving, infections, and malignant neoplasms, including lymphoma.We hereby present a case of 50 year old woman who presented with fatigue and loss of appetite since a yearalong with bilateral pedal edema and breathlessness.

Item Type: Article
Uncontrolled Keywords: Anorexia nervosa; cytopenias; cachexia; serous atrophy.
Subjects: Medicine > MMMC Manipal > Pathology
Medicine > KMC Manipal > Pathology
Depositing User: KMC Manipal
Date Deposited: 17 Jun 2015 11:32
Last Modified: 17 Jun 2015 11:32

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