A facile synthesis of N-substituted 2,5-dimethylpyrroles with saccharin as a green catalyst

Namratha, B and Gaonkar, Santosh L (2015) A facile synthesis of N-substituted 2,5-dimethylpyrroles with saccharin as a green catalyst. Chemistry of Heterocyclic Compounds, 51 (4). pp. 320-323.

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Abstract

The paper describes a convenient method for the preparation of N-substituted 2,5-dimethylpyrroles using edible sweetener saccharin. Various heterocyclic and aromatic hydrazides have been converted to their corresponding Paal–Knorr pyrroles at room temperature in methanol with saccharin as a green catalyst. Saccharin can be recycled for the next two runs without apparent loss in its activity. Here we propose a method which is speedy, proficient, and ecologically safe

Item Type: Article
Uncontrolled Keywords: pyrrole, saccharin, cyclocondensation, Paal–Knorr reaction.
Subjects: Engineering > MIT Manipal > Chemistry
Depositing User: MIT Library
Date Deposited: 22 Jun 2015 06:28
Last Modified: 22 Jun 2015 06:28
URI: http://eprints.manipal.edu/id/eprint/143108

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