Hemolytic Uremic Syndrome- a rare complication of viper envenomation

Boloor, Archith and Rao, Jagadish Padubidri and Rasal, Yogesh Prakash (2015) Hemolytic Uremic Syndrome- a rare complication of viper envenomation. The Journal of Karnataka Medico-Legal Society , 24 (1). pp. 34-35.

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Abstract

The triad of acute renal failure, thrombocytopenia and haemolytic anaemia with schistocytes(fragmented erythrocytes) comprise the Haemolytic Uraemic Syndrome (HUS).Its pathogenesis involves an activation/lesion of microvascular endothelial cells, mainly in the renal vasculature, secondary to bacterial toxins, drugs, or autoantibodies. Less frequently, renal microthrombi are due to an acquired or a constitutional deficiency in ADAMTS-13, the protease cleaving VonWilebrand factor H. In adults, several HUS are encountered in the course of chronic nephropathies: nephroangiosclerosis, chronic glomerulonephritis, post irradiation nephropathy, scleroderma, disseminated lupus erythematosus, antiphospholipid syndrome, and toxins. Coagulopathy is the commonest important, systemic clinical syndrome caused by snake envenoming in the world, and venom-induced consumption coagulopathy (VICC) is the most clinically important coagulopathy but rare , because it can be complicated by serious and life-threatening haemorrhage .We report a rare case of a farmer developing HUS after 48 hours following Viper bite.

Item Type: Article
Uncontrolled Keywords: Viper bite, consumptive coagulopathy, thrombotic microangiopathy
Subjects: Medicine > KMC Mangalore > Forensic Medicine
Depositing User: KMCMLR User
Date Deposited: 02 Jul 2015 11:10
Last Modified: 02 Jul 2015 11:10
URI: http://eprints.manipal.edu/id/eprint/143219

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