Correlation of Ischemia Modified Albumin and Advanced Oxidation Protein Products with lipid profile: A Possible link to cardiovascular diseases

Surendran, Sudarshan (2015) Correlation of Ischemia Modified Albumin and Advanced Oxidation Protein Products with lipid profile: A Possible link to cardiovascular diseases. International Journal of Biochemistry, 197. pp. 447-454. ISSN 4438-5728

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Abstract

Aim: To evaluate the presence of a correlation between Ischemia Modified Albumin (IMA) and Advanced Oxidation Protein Products (AOPP) to cardiovascular diseases. Study design: Our study was designed to evaluate any link between the levels of IMA and AOPP with other risk factors known to increase risk of cardiac diseases (such as lipid profile). Place and duration of the study: This study was conducted by including the patients visiting Father Muller Medical College Hospital, Mangalore, Karnataka, India. The study was conducted for one year from May 2012 to April 2013. Methodology: A total of 151 participants were categorized into normal, prehypertension and hypertension groups. They were assessed for their levels of AOPP and IMA, and then these values were correlated to various other basic parameters. Results: On a whole, when the results of all the three groups were combined and AOPP correlated with the BMI, lipid profile values and IMA, a significant positive correlation (P<0.05) was seen with BMI, LDL (bad cholesterol), Triglycerides, TCHOL: HDL ratio, and NONHDL. Conclusion: The increase in IMA and AOPP levels indicate a positive correlation with most of the lipid profile values, which are known risk factors in cardiovascular diseases.

Item Type: Article
Uncontrolled Keywords: Cardiovascular diseases; Hypertension; Advanced oxidation protein products; Ischemia modified albumin; Free radicals; Lipid profile; Blood pressure.
Subjects: Medicine > MMMC Manipal > Anatomy
Depositing User: KMC Manipal
Date Deposited: 20 Jul 2015 07:06
Last Modified: 20 Jul 2015 07:06
URI: http://eprints.manipal.edu/id/eprint/143362

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