Acanthamoeba meningoencephalitis in immunocompetent: A case report and review of literature

Khanna, Vinay and Shastri, BA and Gopinathan, Anusha and Mukhopadhayay, Chiranjay and Khanna, Ruchee (2014) Acanthamoeba meningoencephalitis in immunocompetent: A case report and review of literature. Tropical Parasitology, 4 (2). pp. 115-118. ISSN 2229-5070

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A 30-year-dd manual laborer from Karnataka, India presented with intermittent low grade fever and diffuse headache for 1 month. On examination, patient had enlarged supraclavicular and cervical lymph nodes. Patient had positive Kernig's sign and neck stiffness. Motor, sensory and cranial nerve examinations were within the normal limits. Alxlominal, cardiovascular and chest examination did not yield any positive findings. Contrast enhanced computed tomography head was normal. Patient was suspected to have extrapulmonary tuberculosis. Patient was started on antitubercular drugs. Diagnostic lumbar puncture was performed. Wet mount and Giemsa smear preparation of cerebrospinal fluid (CSF) showed trophozoites suggestive of Acanthamoeba. CSF was cultured onto non-nutrient agar with an overlay of Escherichia coli. Wet mount made from the culture media yielded cysts and trophozoites of Acanthamoeba spp. Patient was diagnosed with Acanthamoeba meningitis and was started on specific therapy with Rifampicin 600 mg once a day, Cotrimoxazole 960 mg twice-a-day and Fluconazole 400 mg once daily for 2 weeks. Patient had a complete recovery and was discharged from the hospital.

Item Type: Article
Uncontrolled Keywords: Acanthamoeba spp; immunocompetant; meningoencephalitis.
Subjects: Medicine > KMC Manipal > Medicine
Medicine > KMC Manipal > Microbiology
Medicine > KMC Manipal > Pathology
Depositing User: KMC Manipal
Date Deposited: 20 Jul 2015 10:21
Last Modified: 20 Jul 2015 10:21

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