Multidrug and Extensively Drug-resistant Tuberculosis from a General Practice Perspective

Yashodhara, BM and Huat, Choo Beng and Naik, Lakshmi Nagappa and Umakanth, Shashikiran and Hande, Manjunatha H (2010) Multidrug and Extensively Drug-resistant Tuberculosis from a General Practice Perspective. Infection and Drug Resistance. pp. 115-122.

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Despite intensive efforts to eradicate the disease, tuberculosis continues to be a major threat to Indian society, with an estimated prevalence of 3.45 million cases in 2006. Emergence of multidrug-resistant tuberculosis has complicated eradication attempts in recent years. Incomplete and/inadequate treatment are the main causes for development of drug resistance.Directly observed therapy, short-course (DOTS) is the World Health Organization (WHO) strategy for worldwide eradication of tuberculosis, and our country achieved 100% coverage for DOTS through the Revised National Tuberculosis Control Program in 2006. For patients with multidrug-resistant tuberculosis, the WHO recommends a DOTS-Plus treatment strategy. Early detection and prompt treatment of ultidrug-resistant tuberculosis is crucial to avoid spread of the disease and also because of the chances of development of potentially incurable extensively drug-resistant tuberculosis in these cases. This review discusses the epidemiologic, diagnostic, and therapeutic aspects of multidrug-resistant tuberculosis, and also outlines the role of primary care doctors in the management of this dangerous disease.

Item Type: Article
Uncontrolled Keywords: Multidrug-resistant; Extensively drug-resistant; Tuberculosis; General practice
Subjects: Medicine > MMMC Maleka
Medicine > KMC Manipal > Medicine
Depositing User: KMC Manipal
Date Deposited: 24 Jul 2015 04:20
Last Modified: 24 Jul 2015 04:20

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