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A prospective comparison of two regimes of bowel preparation for pediatric colorectal procedures: normal saline with added potassium vs. polyethylene glycol

Chattopadhyay, Anindya and Bhanu, Prakash and Vepakomma, Deepti and Nagendhar, Yoga and Vijay, Kumar (2004) A prospective comparison of two regimes of bowel preparation for pediatric colorectal procedures: normal saline with added potassium vs. polyethylene glycol. Pediatric Surgery International, 20. pp. 127-129. ISSN 0179-0358

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Abstract

We prospectively evaluated the safety 'and efficacy of total gut irrigation (TGI) using normal saline with added potassium (NS) and polyethylene glycol (PG) in patients undergoing a variety of colorectal procedures including single-stage pull-through for Hirschsprung's disease (HD), Fifty-four patients were randomly assigned into one of the two groups (NS or PG), Pre- and post-TGI weight, abdominal girth, and serum electrolytes were assessed. Patients were also evaluated for vomiting and abdominal discomfort. At surgery, bowel preparation was evaluated, and postoperative complications were recorded. Both NS and PG are safe and effective agents for TGI. No patient in either group had any clinical or statistically significant change in the evaluated parameters. The amount of NS required for TGI was significantly higher than PG, and PG was better tolerated than NS. All patients with HD completed TGI, although one patient with long' segment HD had abdominal distension high-fiber diet [2]. In the last few years, total gut irrigation (TGI) using polyethylene glycol ePG) has been shown to be safe and effective in bowel preparation in the pediatric population [3]. TGI using normal saline with added potassium (NS) or Hartmann's solution has also shown good results [2,3]. However, there are reports of electrolyte shifts with NS [3,4] and also with PG in infants [5]. We undertook a prospective study to evaluate the safety and efficacy of TGI using PG versus NS, and also used TGI for children undergoing single-stage surgery for Hirschsprung's disease (HD) in order to establish the safety profile and the place of such a regime in the bowel preparation for these small patients. Our ,institute's ethics committee cleared the study.

Item Type: Article
Uncontrolled Keywords: Total gut irrigation; Polyethylene glycol; Colorectal procedures; Hirschsprung's disease.
Subjects: Medicine > KMC Manipal > Paediatric Surgery
Depositing User: KMC Manipal
Date Deposited: 06 Aug 2015 06:11
Last Modified: 06 Aug 2015 06:11
URI: http://eprints.manipal.edu/id/eprint/143771

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