Acute kidney injury in post cardiac surgery - An evaluation with eGFR (Estimated glomerular filtration rate) and akin criteria

Ummer, Saleena V and Raghavan, Vivek and Kamath, Ganesh S and Kamath, Asha and Nalini, K and Gopalakrishna, K (2014) Acute kidney injury in post cardiac surgery - An evaluation with eGFR (Estimated glomerular filtration rate) and akin criteria. WebmedCentral Clinical Biochemistry, 5 (12). pp. 1-14. ISSN 2046-1690

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Abstract

Acute Kidney Injury (AKI) is one of the major complications of cardiac surgery affecting 17% to 45% of the cardiac surgical patients. It is associated with high morbidity and mortality. Prevention and management of AKI in post cardiac surgery is still a matter of concern due to the lack of early markers. This study was designed as a single centered retrospective cohort study aimed to find out the proportion of the kidney injury in patients who underwent cardiac surgery and to evaluate the efficiency of eGFR and AKIN criteria for the early prediction of AKI. The retrospective data of consecutive patients (January 2008 to November 2013), were collected and analyzed. Diagnosis of kidney injury was confirmed by a serum creatinine level > 1.4mg/dL. Out of 301 patients (aged between 18 to 75 years) studied 26.5% were diagnosed with AKI. AKIN criteria identified 31.3% with AKI and based on eGFR it was 29.2%. Our findings suggest that, both AKIN and eGFR estimations may be useful for earlier detection of AKI than serum creatinine. The high incidence of AKI associated with cardiac surgery should prompt the inclusion of these parameters in the prediction of kidney damage to identify patients at increased risk for the timely management and patient care.

Item Type: Article
Uncontrolled Keywords: Acute Kidney Injury; Cardiac Surgery; Estimated Glomerular Filtration Rate; AKIN criteria; RIFLE criteria.
Subjects: Allied Health > MCOAHS Manipal > Medical Laboratory Tech
Medicine > KMC Manipal > Biochemistry
Medicine > KMC Manipal > Community Medicine
Medicine > KMC Manipal > Cardiovascular & Thoracic Surgery
Depositing User: KMC Manipal
Date Deposited: 12 Aug 2015 06:41
Last Modified: 12 Aug 2015 06:41
URI: http://eprints.manipal.edu/id/eprint/143854

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