Identification of Mortality-related Predictive Factors in Hospitalized Patients with Ischemic Stroke

Mittal, Saumya H and Goel, Deepak and Mittal, Manish and Govil, Tuhina and Mittal, Salony (2015) Identification of Mortality-related Predictive Factors in Hospitalized Patients with Ischemic Stroke. Astrocyte, 1 (4). pp. 272-276.

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Abstract

Objective: This prospective study was planned to study the prognostic value of time to presentation to the hospital, clinical scales and examination, hematological and biochemical parameters as predictive factors of mortality in ischemic stroke. Materials and Methods: In this study, 188 consecutive patients of ischemic stroke were included. The patients were subjected to relevant history taking, clinical evaluation, blood investigations (total leukocyte count [TLC], capillary blood sugar, potassium, high‑sensitivity C‑reactive protein (hs‑CRP), troponin I (Trop I)), electrocardiogram (ECG) and neuroimaging. The patients were followed up till their final outcome in the hospital, and patients who expired were grouped as ‘Mortality Group’ and the rest as ‘Discharged Group’. Logistic regression analysis was carried out among the significant parameters to identify independent predictors of mortality in cases of ischemic stroke. Results: After statistical analysis, it was found that late presentation to the hospital, pyrexia (temperature >99°F), low diastolic blood pressure at the time of admission, hypoxia (saturation of oxygen [sPo2] <94%), National Institute of Health Science scale (NIHSS) score >15, modified Rankin score (MRS) greater than 3, Glasgow coma scale (GCS) less than 8, hyperglycemia (random blood sugar >200 mg/dL), raised total leukocyte count and hs‑CRP (>10 mg/L), are positive predictive factors of mortality in cases of ischemic stroke. Conclusion: Late presentation to the hospital, pyrexia (temperature >99°F), low diastolic blood pressure at the time of admission, hypoxia (sPo2 <94%), more severe stroke (NIHSS score >15, MRS >3, GCS <8), high TLC estimated at the time of hospitalization, are the most important predictive prognostic factors of in‑hospital mortality in cases of ischemic stroke.

Item Type: Article
Uncontrolled Keywords: In-hospital mortality, ischemic stroke, predictive factors
Subjects: Medicine > KMC Mangalore > Neurology
Depositing User: KMCMLR User
Date Deposited: 18 Sep 2015 16:40
Last Modified: 18 Sep 2015 16:40
URI: http://eprints.manipal.edu/id/eprint/143942

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