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Serum Lactate Dehydrogenase in Non-Hodgkin’s Lymphoma: A Prognostic Indicator

Yadav, Charu and Ahmad, Afzal and D’Souza, Benedicta and Agarwal, Ashish Chandra and *, Nandini M and Shenoy, Ashok K and D’Souza, Vivian (2015) Serum Lactate Dehydrogenase in Non-Hodgkin’s Lymphoma: A Prognostic Indicator. Indian Journal of Clinical Biochemistry. ISSN 0970-1915

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Abstract

Non-Hodgkin’s lymphoma constitutes a group of disorders originating from the malignant transformation of lymphocytes and involving either the lymph nodes or extranodal sites. NHL commonly presents in the sixth to seventh decade of life with a male preponderance (50–75 %). Recent studies have shown importance of serum LDH in prognosis of NHL. Authors report a case of a 63 year old male presenting with complaints of fever and backache for past 4 months. General and systemic examination revealed bilateral axillary lymphadenopathy and splenomegaly respectively. Serum LDH level was highly elevated (3441 U/l). Excisional axillary and bone marrow biopsy were done before oncology referral. Complete workup revealed diffuse Non-Hodgkin’s lymphoma with bone marrow infiltration. Patient died because of acute renal failure due to NHL and DM 2 (Type 2 diabetes mellitus).

Item Type: Article
Uncontrolled Keywords: Lactate dehydrogenase (LDH) � Non- Hodgkin’s lymphoma (NHL)
Subjects: Medicine > KMC Mangalore > Biochemistry
Depositing User: KMCMLR User
Date Deposited: 18 Sep 2015 16:40
Last Modified: 18 Sep 2015 16:40
URI: http://eprints.manipal.edu/id/eprint/143955

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