Determination of saturated solubility of naproxen using UV visible spectrophotometer

Kumar, Lalit and Suhas, BS and Pai, Girish K and Verma, Ruchi (2015) Determination of saturated solubility of naproxen using UV visible spectrophotometer. Research Journal of Pharmacy and Technology, 8 (7). pp. 825-828. ISSN 0974-3618

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Abstract

Solubility of the drug plays a crucial role in the formulation and development of the drug. Assessing the solubility of the drug is one of the most important parameter in pre-formulation. Parenteral formulations require sufficient solubility of the drug molecules. Correspondingly bioavailability from solid formulations like tablets and capsules is also dependent on solubility and permeability. The objective of this study was to investigate the solubility of drug in different pH medium using UV visible spectrophotometer. The drug solubility was studied in the pH range 1.2 to 7.4. This study concludes that the naproxen has pH dependent solubility.

Item Type: Article
Uncontrolled Keywords: Saturated Solubility; UV Visible Spectrophotometer; Naproxen; pH range.
Subjects: Pharmacy > MCOPS Manipal > Pharmaceutical Chemistry
Pharmacy > MCOPS Manipal > Pharmaceutics
Depositing User: KMC Library
Date Deposited: 28 Sep 2015 09:12
Last Modified: 28 Sep 2015 09:12
URI: http://eprints.manipal.edu/id/eprint/144184

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