Microalbuminuria - A Better Marker in Hypertensive Disorders of Pregnancy

*, Ruby P. Babu and *, Alap Christy and Hegde, Anupama and Manjrekar, Poornima and *, Maria Joseph Kurian (2015) Microalbuminuria - A Better Marker in Hypertensive Disorders of Pregnancy. Saudi Journal of Kidney Diseases and Transplantation, 26 (5). pp. 941-946. ISSN 1319-2442

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Abstract

To assess the role of microalbuminuria in pre-eclampsia (PE) as a diagnostic marker, we studied 40 PE cases and 40 normotensive controls at 24 ± 4 weeks of gestation in women 20–35 years of age. The patients with PE had significant microalbuminuria in comparison with the controls, in addition to deranged renal function tests. The receiver operating characteristic curve showed that microalbuminuria had the highest sensitivity (100%) and good specificity (77.6%). Microalbuminuria had the highest area under the curve (0.869) for both diagnosis of PE and renal function assessment. Microalbuminuria also had a good correlation with systolic blood pressure in the cases with mild grades of renal dysfunction. Microalbuminuria is a specific marker in PE and it also helps to assess the renal function status. Therefore, microalbuminuria may be used in the early diagnosis and management of PE patients in order to reduce the immediate and long-term complications.

Item Type: Article
Subjects: Medicine > KMC Mangalore > Obstetrics & Gynaecology
Medicine > KMC Mangalore > Biochemistry
Depositing User: KMCMLR User
Date Deposited: 28 Sep 2015 12:03
Last Modified: 28 Sep 2015 12:03
URI: http://eprints.manipal.edu/id/eprint/144198

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