Spectrum of imaging findings in paget’s disease of the breast — A pictorial review

Sripathi, Smiti and Ayachit, Anurag and Rajagopal, KV and Kumar, Sandeep (2015) Spectrum of imaging findings in paget’s disease of the breast — A pictorial review. Insights Imaging, 6 (4). pp. 419-429. ISSN 1869-4101

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Abstract

Purpose: We aimed to demonstrate imaging features of Paget’s disease of breast, which is an extremely uncommon malignancy that presents with changes in the nipple-areolar region that may or may not be associated with an underlying in situ component or invasive cancer. Methods and Results : Mammography is the initial investigation of choice, having a high sensitivity especially in cases where a palpable mass is present. The addition of ultrasound improves the accuracy of mammography. When both mammography and ultrasound are negative, MRI may detect an underlying mass or ductal carcinoma in situ (DCIS). Conclusion : The surgical management of Paget’s disease includes mastectomy with or without axillary dissection, though breast conservation surgery in the form of wide local excision can also be done in a selected group of patients. Management should be based on both clinical and imaging findings, including mammography and ultrasound, with MRI playing a crucial role in defining the extent of involvement.

Item Type: Article
Additional Information: Pictorial Review
Uncontrolled Keywords: Paget’s; Nipple ; DCIS ; Invasive ; Malignancy.
Subjects: Medicine > KMC Manipal > Radiology
Depositing User: KMC Library
Date Deposited: 10 Oct 2015 09:25
Last Modified: 10 Oct 2015 09:25
URI: http://eprints.manipal.edu/id/eprint/144384

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