PRES and PLEDS: An Uncommon Association

Mittal, Saumya H and Pai, Shivanand and *, Rakshith KC and *, Misri Z K and Shenoy, Nisha (2015) PRES and PLEDS: An Uncommon Association. EC Neurology, 2 (2). pp. 83-86.

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Posterior reversible encephalopathy syndrome (PRES) or reversible posterior leucoencephalopathy syndrome is a relatively new entity having been described first in 1996 by Hinchey. The most common manifestations of this syndrome are headache, visual defects, altered sensorium and frequently seizures. EEG in these patients shows a diffuse slowing of waves- theta or delta waves are seen. Focal EEG pathologies may be seen in cases with focal seizures. Seizure activity recorded may also include focal or generalized spikes, spike wave pattern or sharp spikes. We present our case who presented with myoclonic seizures, and not with the usually expected generalized tonic clonic seizures. Besides, the myoclonic jerking persisted beyond 24 hours, and this is usually unexpected. Most patients become seizure free spontaneously or within 24 hours of the onset of antiepileptic medicines. Also, chronic kidney disease is not a commonly considered cause of PRES. Most patients of chronic kidney disease that develop this syndrome are on dialysis. The patients usually do not show periodic lateralized epileptiform discharges. Our patient showed PLEDs in her EEG. And in our review, only one report was found of a patient having developed epilepsy after PRES. That patient however had recurrent PRES, while our patient had the first episode of PRES.

Item Type: Article
Uncontrolled Keywords: Encephalopathy; Hyperintensity; Sensorium; Epilepsy
Subjects: Medicine > KMC Mangalore > Medicine
Depositing User: KMCMLR User
Date Deposited: 26 Oct 2015 15:59
Last Modified: 26 Oct 2015 15:59

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