Khanna, Vinay and Bairy, Indira and Maradi, Ravindra (2012) Comparision Between Avidity Test and Detuned Elisa Test in Detecting the Recent and Established hiv-1 Infection. International Journal of Pharma and Bio Sciences, 3 (4). 865 -873. ISSN 0975-6299

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Abstract

Identifying patients with early human immunodeficiency virus infection is an important public health goal. Those individuals who have acquired human immunodeficiency virus infection recently have high viral loads both in their blood and genital secretions, thus facilitating transmission. Identifying and intervening these individuals early in the course of their disease, helps to reduce onward transmission.The current study is undertaken, comparing the Avidity test and Detuned ELISA which are modified immunoassays to detect recent and established HIV infection. The study was conducted in 261 HIV-1 seropositive patients aged more than 15 years of age. Data was analyzed using SPSS 16.0 andvariables are compared by using chi square test. There were a total of 33 cases detected by detuned immunoassay with value ≤1 and 26 cases detected by Avidity test with value ≤0.9 as recent cases. 96.55% of concordance was found between Avidity test and Detuned ELISA.

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