Six percent hetastarch versus lactated Ringer’s solution – for preloading before spinal anesthesia for cesarean section

Upadya, Madhusudan and Bhat, Sonal and Paul, Seema (2016) Six percent hetastarch versus lactated Ringer’s solution – for preloading before spinal anesthesia for cesarean section. Anesthesia: Essays and Researches, 10 (1). pp. 33-37. ISSN 0259-1162

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Abstract

Background: Regional anesthesia has been the choice of preference for elective cesarean sections. This study was designed to determine whether preoperative administration of 6% hetastarch decreases the incidence of hypotension. Materials and Methods: This study was conducted on 50 nonlaboring American Society of Anesthesiologists class I and II women undergoing elective cesarean section. Patients were randomly divided into two groups and were preloaded either with 1000 ml Ringer’s lactate (RL) or 500 ml of 6% hetastarch 30 min prior to the surgery. Spinal anesthesia was performed with patients in the left lateral position and 2 cc (10 mg) of 0.5% of bupivacaine injected into subarachnoid space. Hemodynamic variables (heart rate, noninvasive blood pressure, and SpO2) were recorded from prior to preloading until the recovery from the subarachnoid blockade. Results: Our study showed the incidence of hypotension to be 28% in the hetastarch group and 80% in the RL group. Rescue ephedrine requirements for the treatment of hypotension were significantly less in patients who were preloaded with 6% hetastarch prior to cesarean section. The neonatal outcome, as determined by Apgar scores was good and similar in both groups. Conclusion: Hence, we conclude that 6% hydroxyl ethyl starch is more effective than lactated Ringers solution and that its routine use for preloading prior to spinal anesthesia should be considered.

Item Type: Article
Uncontrolled Keywords: Cesarean, preloading, spinal
Subjects: Medicine > KMC Mangalore > Anaesthesiology
Depositing User: KMCMLR User
Date Deposited: 29 Jan 2016 10:18
Last Modified: 29 Jan 2016 10:18
URI: http://eprints.manipal.edu/id/eprint/145155

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