Urinary Tract Infection Treatment Pattern of Elderly Patients in a Tertiary Hospital Setup in South India: A Prospective Study

Katta, Ramanath Venkatesh and Prabhu, Mukhyaprana M and Nandakumar, Krishnadas and Pai, Sreedhara KR (2016) Urinary Tract Infection Treatment Pattern of Elderly Patients in a Tertiary Hospital Setup in South India: A Prospective Study. Journal of Young Pharmacists, 8 (2). pp. 108-113.

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Abstract

Introduction: Urinary tract infections (UTIs) are more common in geriatrics due to physiological alterations/pathological conditions. The main objective of this study was to analyze the incidence, causative organisms, types of antibiotics used, drug interactions, the antibiotic cost, and its outcome. Method: This is across-sectional study conducted in selected medicine units over a period of 18 months. The enrolled patient’s therapy pattern spotted from the admission to discharge. The mandatory patients provided with pharmaceutical care services. Results and Discussion: Among 475 observed cases, 106 patients had UTIs (22.31%). The mean number of drug were 7.42 ± 2.31per prescription. Out of 106 prescriptions, 63 prescriptions had drug interactions. The drug interactions degree varied from mild (12.63%), moderate (60.3%) and severe (26.58%) remained managed by spacing intervals, alternate drug use, and close monitoring techniques. Strangely, all comorbid UTI patient outcomes showed improvement. The antibiotic cost of the management ranged from $ 0.21-160.8 with a median of $ 26.30 and the common organisms were E. coli (48%), Enterococcus (16%). The average length of patient hospital stay was 11.65 ± 8.94 days. Conclusion: This study showed that about one-fourth patients have UTIs and half of them were affected by E. coli. Hence, this study proposes the paucity and its implication of pharmaceutical care service research studies, on health-hygiene, proper use of antibiotics & its cost minimization; untoward interactions cost prevention, for better outcome in India.

Item Type: Article
Uncontrolled Keywords: Urinary tract infection (UTI); Drug interaction (DI); Geriatrics; Hypertension( HTN); Discharge against medical advice (DAMA); Tricyclic antidepressants (TCA); HCT: Hydrocholrothiazide
Subjects: Medicine > KMC Manipal > Medicine
Pharmacy > MCOPS Manipal > Pharmacology
Depositing User: KMC Library
Date Deposited: 10 Mar 2016 15:15
Last Modified: 10 Mar 2016 15:15
URI: http://eprints.manipal.edu/id/eprint/145531

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