An Outbreak of Burkholderia cepacia Bacteremia in a Neonatal Intensive Care Unit

Paul, Liz Mary and Hegde, Ashwini and Pai, Tanvi and Shetty, Subodh and Baliga, Shrikala and Shenoy, Suchitra M (2016) An Outbreak of Burkholderia cepacia Bacteremia in a Neonatal Intensive Care Unit. Indian Journal of Pediatrics, 83 (4). pp. 285-288. ISSN 0019-5456

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Abstract

Objectives To identify the source of infection, to study the clinical profile and outcomes of neonates with Burkholderia septicemia and to determine the antimicrobial susceptibility patterns of the isolates. Methods The authors describe a 3 mo outbreak of nosocomial Burkholderia cepacia bacteremia involving 12 neonates. During the outbreak, ventilator humidifier water, intravenous solutions and other possible sources were taken from the concerned neonatal intensive care units (NICUs); cultured and isolates identified by standard microbiological techniques and VITEK system. Clinical details of affected babies were also obtained to ascertain the clinical significance of the isolates. Results All neonates had clinical and biochemical evidence of sepsis and the source could be tracked to intravenous solutions of 5 % dextrose, normal saline (opened bottles) and continuous positive airway pressure humidifier water. Strain relatedness of the environmental isolates with the clinical isolates is likely as antibiotic susceptibility patterns were similar. Conclusions The investigations revealed the source of the nosocomial outbreak which is crucial for initiating appropriate control measures.

Item Type: Article
Uncontrolled Keywords: Burkholderia . Bacteremia . Neonate . Outbreak
Subjects: Medicine > KMC Mangalore > Microbiology
Medicine > KMC Mangalore > Paediatrics
Depositing User: KMCMLR User
Date Deposited: 22 Mar 2016 09:47
Last Modified: 22 Mar 2016 09:47
URI: http://eprints.manipal.edu/id/eprint/145621

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