Immune Mediated Crescentic MPGN Secondary to HBV Infection: A Rare Presentation for a Common Infection

Mareddy, Aswani Srinivas and Rangaswamy, Dharshan and Prabhu, Ravindra A and Nagaraju, Shankar Prasad and Koti, Neeraja (2016) Immune Mediated Crescentic MPGN Secondary to HBV Infection: A Rare Presentation for a Common Infection. Australasian Medical Journal, 9 (1). pp. 12-16.

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Abstract

Hepatitis B virus (HBV) infection presenting as crescentic glomerulonephritis in the absence of cryoglobulinemia is an extremely rare phenomenon. We report a case of a 44-yearold male with HBV infection, who underwent kidney biopsy for rapidly progressive renal failure and nephrotic range proteinuria. Histopathological evaluation of the kidney biopsy was consistent with immune complex mediated crescentic membranoproliferative glomerulonephritis (MPGN). The patient achieved complete renal and virological remission with steroids, plasmapheresis and antiviral therapy. This case report summarises the importance of early initiation of immunosuppression and plasmapheresis under antiviral coverage for improved clinical outcomes.

Item Type: Article
Uncontrolled Keywords: Hepatitis B Virus; Crescentic glomerulonephritis; Crescentic membranoproliferative glomerulonephritis; MPGN
Subjects: Medicine > KMC Manipal > Medicine
Medicine > KMC Manipal > Nephrology
Depositing User: KMC Library
Date Deposited: 09 Apr 2016 11:46
Last Modified: 09 Apr 2016 11:46
URI: http://eprints.manipal.edu/id/eprint/145797

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