Review on Estimation of Correlation between Various Pixel Intensities of Microarray Spots

Karun, Kalesh M and Binu, VS (2015) Review on Estimation of Correlation between Various Pixel Intensities of Microarray Spots. Arya Bhatta Journal of Mathematics and Informatics, 7 (2). pp. 283-286. ISSN 2394-9309

[img] PDF
Review correlation Aryabhata journal.pdf - Published Version
Restricted to Registered users only

Download (3MB) | Request a copy

Abstract

In cDNA microarray experiments, the measurement of interest is signal intensity ratio of spots. Each spot have four types of pixel intensities namely red foreground, green foreground, red background and green background. The uncertainty associated with the signal intensity ratio depends on the correlation between pixel intensities of spots. It is important to estimate these correlations of pixel intensities of spots to propagate the uncertainty associated with the intensity ratio as well as to address the systematic errors arise from the chip artifacts. The present study is a review to identify various methods to estimate the correlation of various pixel intensities of microarray spots. Articles published from 1994 to 2015 are searched in various databases like PubMed, Scopus, Web of Science, and Google Scholar. Six articles are selected for the review based on selection criteria. We observed that there is very little literature available which deals with the impotence of the correlation between various pixel intensities of microarray spots.

Item Type: Article
Uncontrolled Keywords: cDNA microarray; Pixel intensities; Intensity ratio; Correlation; Pixel correlation
Subjects: Departments at MU > Statistics
Depositing User: KMC Library
Date Deposited: 06 Jun 2016 09:16
Last Modified: 06 Jun 2016 09:16
URI: http://eprints.manipal.edu/id/eprint/146307

Actions (login required)

View Item View Item