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Endometrial Carcinoma in the young with leiomyomata – Is it a coexistence, an episodic occurrence or an existence of a phenotype?

*, BhavyaAdla and *, Athira Narayanan and Kushtagi, Pralhad (2016) Endometrial Carcinoma in the young with leiomyomata – Is it a coexistence, an episodic occurrence or an existence of a phenotype? Indian Journal of Obstetrics and Gynecology, 4 (2). pp. 185-189. ISSN 2321-1636

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Abstract

Abnormal uterine bleeding is acommon gynecological clinicalproblem. In premenopausal ageuterine leiomyomata are thecommon cause and among thepostmenopausal women the mostworried of is endometrialcarcinoma. Ovarian steroidalhormones do stimulate cellproliferation and extracellularmatrix accumulation initiating orpromoting growth of leiomyocyte. Itis known that ovarian hormones aredependent on receptors for exertingtheir action. Leiomyoma grow evenin patients with no increasedestrogen. Whereas, endometrialcarcinoma is an ovarian hormonedependent tumor with a subtypemore often attributed to anunopposed estrogenic stimulationof endometrium. Reported are 4cases in premenopausal age thatwere detected to have developedendometrial carcinoma in short timeafter the myomectomy.

Item Type: Article
Uncontrolled Keywords: leiomyoma; endometrial carcinoma; premenopausal women; nulligravida; abnormal uterine bleeding
Subjects: Medicine > KMC Mangalore > Obstetrics & Gynaecology
Depositing User: KMCMLR User
Date Deposited: 12 Jul 2016 14:49
Last Modified: 12 Jul 2016 14:49
URI: http://eprints.manipal.edu/id/eprint/146557

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