Idiopathic intracranial hypertension: Clinical profile and outcome

Pai, Shobha G and Sharma, Trisha and Gupta, Richa (2016) Idiopathic intracranial hypertension: Clinical profile and outcome. Journal of Clinical Ophthalmology and Research, 4 (1). pp. 25-29. ISSN 2320-3897

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Abstract

Background: It has been a long standing challenge to clinicians and investigators to explain the pathophysiology of Idiopathic Intracranial Hypertension (IIH).Therefore, the goal of this study is to delineate the clinical course of this disorder. Aim: To delineate the clinical course of Idiopathic Intracranial Hypertension with an emphasis on visual prognosis. Settings and Design: Prospective, observational study of 18 patients. Materials and Methods: Patients with unilateral or bilateral disc oedema; CSF pressure >25 cm H2O non- focal neurological examination, and normal CT/MRI/MRV scans were included in the study, while those with concurrent ocular disease were excluded .Ocular examination, visual acuity, fundus photography and visual fields evaluation was done at presentation and during follow up visits for a period of two years. Statistical analysis: Descriptive study. Results: Of the 18 patients, 16 were females. The average age of onset was 31.5 years. Hypertension was the most common systemic comorbidity, seen in 5 patients. Headache was the most common presenting symptom, seen in all 18 patients. Diminution of vision was seen in 16 eyes, out of which 14 improved while 2 showed progressive impairment of vision. Abnormal visual field tests included an enlarged blind spot in 11 out of 36 eyes and peripheral constriction in 14 out of 36 eyes .17 patients had a bilateral and symmetric disc swelling. A CSF opening pressure of more than 40 cm of H2O was noted in 6 patients. All the patients were managed medically with diuretics therapy (acetazolamide) and weight reduction. Conclusion: A strong suspicion of Idiopathic Intracranial Hypertension in chronic severe headaches and immediate investigations followed by proper treatment can salvage vision of patients even in cases with established papilledema.

Item Type: Article
Uncontrolled Keywords: Idiopathic Intracranial Hypertension, Pseudotumor cerebri, papilledema, headache
Subjects: Medicine > KMC Mangalore > Ophthalmology
Depositing User: KMCMLR User
Date Deposited: 21 Jul 2016 14:34
Last Modified: 21 Jul 2016 14:34
URI: http://eprints.manipal.edu/id/eprint/146678

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