Exercise intolerance in pulmonary hypertension: Mechanism, evaluation and clinical implication

Babu, Abraham S and Arena, Ross and Myers, Jonathan and Padmakumar, R and Maiya, Arun G and Cahalin, Lawrence P and Waxman, Aaron B and Lavie, Carl J (2016) Exercise intolerance in pulmonary hypertension: Mechanism, evaluation and clinical implication. Expert Review of Respiratory Medicine, 10 (9). pp. 979-990.

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Exercise intolerance in pulmonary hypertension (PH) is a major factor affecting activities of daily living and quality of life. Evaluation strategies (i.e., non-invasive and invasive tests) are integral to providing a comprehensive assessment of clinical and functional status. Despite a growing body of literature on the clinical consequences of PH, there are limited studies discussing the contribution of various physiological systems to exercise intolerance in this patient population. Areas covered: This review, through a search of various databases, describes the physiological basis for exercise intolerance across the various PH etiologies, highlights the various exercise evaluation methods and discusses the rationale for exercise training amongst those diagnosed with PH. Expert commentary: With the growing importance of evaluating exercise capacity in PH (class 1, Level C recommendation), understanding why exercise performance is altered in PH is crucial. Thus, the further study is required for better quality evidence in this area

Item Type: Article
Subjects: Allied Health > MCOAHS Manipal > Physiotherapy
Medicine > KMC Manipal > Cardiology
Depositing User: Mr AS Babu
Date Deposited: 31 Aug 2016 09:09
Last Modified: 31 Aug 2016 09:09
URI: http://eprints.manipal.edu/id/eprint/146867

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