Muscle Disorders: A Profile of Patients Undergoing Biopsy in a Tertiary Care Teaching Hospital in South India

Mittal, Saumya H and Chakrobarty, Shreejit and Pai, Shivanand and *, Rakshith KC and *, Misri Z K and Mittal, Salony and Shenoy, Nisha (2016) Muscle Disorders: A Profile of Patients Undergoing Biopsy in a Tertiary Care Teaching Hospital in South India. EC Neurology, 3 (4). pp. 425-427.

[img] PDF
Muscle Disorders- A Profile of Patients Undergoing Biopsy in a Tertiary Care Teaching Hospital in South India.pdf - Published Version
Restricted to Registered users only

Download (232kB) | Request a copy

Abstract

Objective: To correlate the muscle biopsy reports with the clinical profile of the patients. Materials and Methods: Demographic data, presenting symptoms, neurological features, and investigations in 33 patients who underwent muscle biopsy over a period of 3 years in our tertiary care centre were evaluated. Results: Over a period of three years, 33 patients underwent muscle biopsy in our tertiary care hospital. Of these there were 16 females and 17 males. The mean age of the patients was found to be 36.81 years. Most common symptom (28 of the 33) was proximal weakness followed by myalgia (15 of 33 patients). The CPK levels were raised in 27 of the 33 patients and 6 patients had normal levels. The EMG done in all the patients showed myopathic pattern. Of the biopsy reports, 6 were found to have inflammatory myopathy (5 of whom were found to have polymyositis) while 15 were found to have muscle dystrophies. 3 patients had a myopathic biopsy and only 1 showed neurogenic changes. The remaining 4 were normal. Conclusion: Muscle biopsy is considered the gold standard in diagnosis of inflammatory myopathies and muscular dystrophies.

Item Type: Article
Uncontrolled Keywords: Muscle Biopsy; Inflammatory myopathy; Muscle Dystrophies
Subjects: Medicine > KMC Mangalore > Neurology
Depositing User: KMCMLR User
Date Deposited: 14 Sep 2016 12:19
Last Modified: 14 Sep 2016 12:19
URI: http://eprints.manipal.edu/id/eprint/146962

Actions (login required)

View Item View Item