Granular IgM Deposition at Basement Membrane Zone in an Infant with Diffuse Cutaneous Mastocytosis

Kumudhini, Subramanian and Rao, Raghavendra and Salgaonkar, Gauri A and Shetty, Shricharith and Pai, Sathish (2016) Granular IgM Deposition at Basement Membrane Zone in an Infant with Diffuse Cutaneous Mastocytosis. Indian Journal of Dermatology, 61 (5). pp. 581-583. ISSN 0019-5154

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Abstract

Diffuse Cutaneous mastocytosis (DCM) occurs due to abnormal accumulation of mast cells in the skin. We report an 8-month-old infant presented papulovesicular lesions, predominantly on the trunk. Skin biopsy revealed subepidermal bulla, interspersed with mast cells, eosinophils and neutrophils. Direct immunofluorescence microscopy of perilesional skin revealed nonspecific deposition of IgM in granular pattern along the dermoepidermal junction.

Item Type: Article
Uncontrolled Keywords: Diffuse cutaneous mastocytosis; Granular IgM deposition; Vesiculobullous lesions
Subjects: Medicine > KMC Manipal > Dermatology
Medicine > KMC Manipal > Pathology
Depositing User: KMC Library
Date Deposited: 07 Oct 2016 12:02
Last Modified: 07 Oct 2016 12:02
URI: http://eprints.manipal.edu/id/eprint/147088

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