Synthesis and Evaluation of a Series of NSubstituted 2,5-dimethylpyrroles as Anthelmintics and Antibacterials

Gaonkar, Santosh L and Namratha, B and Shetty, Nitinkumar S (2016) Synthesis and Evaluation of a Series of NSubstituted 2,5-dimethylpyrroles as Anthelmintics and Antibacterials. Journal of International Pharmaceutical Research, 8 (3). pp. 25-29. ISSN 1674-0440

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Abstract

A library of N-substituted 2,5-dimethylpyrroles were synthesized from aromatic hydrazides /an amine using saccharin as a green catalyst. The target compounds were screened for their efficacy as anthelmintics and antibacterials in vitro. The results revealed that, compounds 2a, 2b, 2e, 2i, 2k, and 2m were potent anthelmintics while compounds 2a, 2b, and 2k being potent antibacterials

Item Type: Article
Uncontrolled Keywords: anthelmintic, antibacterial, nitroscanate, pyrrole
Subjects: Engineering > MIT Manipal > Chemistry
Depositing User: MIT Library
Date Deposited: 14 Oct 2016 15:29
Last Modified: 14 Oct 2016 15:29
URI: http://eprints.manipal.edu/id/eprint/147135

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