Comparison of clinical profile of geriatric and nongeriatric diabetic patients

Shastry, Rajeshwari and Adhikari, Prabha and Pai, M. R. S. M. and Kotian, MS and Chowta, Mukta N and Ullal, Sheetal D (2015) Comparison of clinical profile of geriatric and nongeriatric diabetic patients. International Journal of Diabetes in Developing Countries, 35 (3). pp. 201-205.

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Abstract

The objective of this study is to compare and evaluate the clinical profile of geriatric and nongeriatric diabetic patients. This is a cross-sectional study conducted in a tertiary care teaching hospital. Patients with type 2 diabetes mellitus were grouped into geriatric (age≥60 years) and nongeriatric (age<60 years). Patients’ demographic data, duration of diabetes, comorbid conditions, medications and laboratory investigations were recorded. Body mass index (BMI) was calculated. Results were analyzed using descriptive statistics. A total of 320 geriatric and 157 nongeriatric diabetics completed the study; mean ages were 68.31±6.06 and 49.91±6.93 years respectively. Significantly, more number of geriatrics had hypertension (78.75 vs 53.5 %) and coronary artery disease (CAD) (31.25 vs 13.37 %) (P=0.0001). There was a significant difference in mean BMI (24.78±3.81 vs 25.89±4.11; P= 0.003), duration of diabetes (11.38±8.90 vs 6.52±5.71; P= 0.001), hypertension (8.40±7.26 vs 5.46±5.67; P=0.001) and peripheral neuropathy (3.67±3.64 vs 2.41±2.27; P=0.034) between the groups. Other co-morbidities and their duration (CAD, dyslipidaemia, nephropathy, retinopathy and hypothyroidism) were similar in both groups. Serum creatinine was significantly higher (but within normal limits) in geriatrics (P=0.0002). Liver enzyme levels were higher in nongeriatric diabetics, while direct bilirubin was higher in geriatrics indicating impaired bilirubin clearance. Geriatrics had significantly higher total cholesterol (180±34.29 vs 163±29.01; P= 0.002) and LDL (105.61±30.43 vs 94.92±25.16; P=0.02). Fasting blood sugar (FBS) was significantly lower in geriatrics (P=0.01); HbA1c too was lower in geriatrics but was not statistically significant. Long-standing diabetes, hypertension and peripheral neuropathy are common among geriatrics. Prevalence of hypertension and CAD is high among geriatric diabetics. Short-time glycemic control (FBS) was better in geriatrics whereas no difference was noted in long-term glycemic control (HbA1c).

Item Type: Article
Uncontrolled Keywords: Geriatrics . Nongeriatrics . Clinical profile . Diabetes mellitus
Subjects: Medicine > KMC Mangalore > Pharmacology
Medicine > KMC Mangalore > Community Medicine
Medicine > KMC Mangalore > Medicine
Depositing User: KMCMLR User
Date Deposited: 12 Nov 2016 14:15
Last Modified: 12 Nov 2016 14:15
URI: http://eprints.manipal.edu/id/eprint/147521

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