Kumar, Pratap and Ravichandran, Subasri Sambandam (2015) Ideal value of serum anti-Mullerian hormone as a predictor of ovarian reserve and outcome in assisted reproductive technology. Fertility Science & Research, 2 (1). pp. 24-28. ISSN 2394-4285

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Abstract

Title of the article: Ideal value of serum anti-Mullerian hormone as a predictor of ovarian reserve and outcome in assisted reproductive technology. Aims: To evaluate serum AMH as a marker of ovarian reserve and reproductive outcome. Settings and Design: Division of Reproductive Medicine, Kasturba Medical College, Manipal University, Manipal, Karnataka, India. Methods and Material: A prospective two year analysis of 84 women undergoing ART with AMH, FSH and AFC measurements was analysed on day 2 of the cycle. The study group was Group I – <0.7, Group II – 0.7 – 3.5, Group III – >3.5 ng/ml. Outcome measures such as the mature oocytes, quality embryos and pregnancy rates were compared between these groups. Statistical analysis used: Non parametric test (Kruskal Wallis), Exact test and ROC curves was used. Results: AMH levels correlated best with age (P = 0.012), antral follicles (P = 0.001), follicles retrieved (P = 0.002) and oocytes obtained (P = 0.041). The number of mature embryos were higher in Group II & III than Group I (P = 0.312). AMH levels were signifi cantly lower in canceled cycles than completed cycles (P = 0.010). The occurrence of OHSS was higher (61%) in Group III and 10% in in Group II (P = 0.001).

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