Disseminated Mycobacterium avium intracellulare complex (MAC) disease in a retropositive patient caused by noncompliance of HAART

Dhar, Kingshuk and Shenoy, Vishnu Prasad and Vishwanath, Shashidhar and Prabhu, Mukhyaprana (2016) Disseminated Mycobacterium avium intracellulare complex (MAC) disease in a retropositive patient caused by noncompliance of HAART. Annals of Tropical Medicine and Public Health, 9 (3). pp. 194-196. ISSN 1755-6783

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Abstract

Mycobacterium avium intracellulare complex (MAC) is the most common mycobacterial cause [after Mycobacterium tuberculosis (MTB)] of an opportunistic disease in human immunodeficiency virus/acquired immune deficiency syndrome (HIV/AIDS) patients with low CD4+ cell count. We report a case of disseminated MAC disease in a 46-year-old retropositive patient, noncompliant to highly active antiretroviral therapy (HAART), with CD4+ T-lymphocyte count of 10 cells/mm3. MAC was isolated in culture from multiple specimens including bone marrow aspirate, blood culture, and bronchoalveolar lavage (BAL) fluid. The patient was successfully treated with the following second-line antitubercular therapies: clarithromycin, rifabutin, and ethambutol.

Item Type: Article
Uncontrolled Keywords: Highly active antiretroviral therapy (HAART); human immunodeficiency virus/acquired immune deficiency syndrome (HIV/AIDS); Mycobacterium avium intracellulare complex (MAC); noncompliance of HAART; nontuberculous mycobacteria (NTM).
Subjects: Medicine > KMC Manipal > Medicine
Medicine > KMC Manipal > Microbiology
Depositing User: KMC Library
Date Deposited: 24 Nov 2016 16:00
Last Modified: 24 Nov 2016 16:00
URI: http://eprints.manipal.edu/id/eprint/147606

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