Synthesis of a series of pyrazoline derivatives carrying tosyl substitution and evaluation of their antimicrobial properties

Shubhalaxmi, . and Manjunatha, B S and Ananda, K and Bhat, Subrahmanya K (2016) Synthesis of a series of pyrazoline derivatives carrying tosyl substitution and evaluation of their antimicrobial properties. Journal of Applied Pharmaceutical Science, 6 (11). pp. 214-217. ISSN 2231-3354

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Abstract

A series of pyrazoline derivatives with tosyloxy substitution were synthesized and characterized. They were evaluated for antimicrobial potential against Mycobacterium smegmatis, gram positive Staphylococcus aureus, gram negative Escherichia coli, and a fungi Candida albicans. The initial screening using zones of inhibition at 50μL concentrations revealed that they are moderately active against the tested strains, and therefore further studies have not been carried out.

Item Type: Article
Uncontrolled Keywords: 2-Pyrazolines; Chalcones; Antimicrobial properties
Subjects: Engineering > MIT Manipal > Chemistry
Depositing User: MIT Library
Date Deposited: 09 Dec 2016 08:55
Last Modified: 09 Dec 2016 08:55
URI: http://eprints.manipal.edu/id/eprint/147670

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