Multiple Intra-renal Pathological Injury Patterns in Resistant Myeloma

Rangaswamy, Dharshan and Madken, Mohit and Prabhu, Ravindra A and Nagaraju, Shankar Prasad (2016) Multiple Intra-renal Pathological Injury Patterns in Resistant Myeloma. Australasian Medical Journal, 9 (9). pp. 308-312. ISSN 1836-1935

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Renal dysfunction in patients with multiple myeloma has a heterogeneous aetiology ranging from pre-renal, intra-renal to post-renal causes. Common pathological forms of paraproteinemic disease include cast nephropathy,amyloidosis and Immunoglobulin chain deposition disease.Infrequently cryoglobulinemic glomerulonephritis and light chain proximal tubulopathy have also been described. The presence of multiple intra-renal pathological injury patterns has been described only once previously with immunoglobulin light chains. We report a patient with long standing treatment resistant multiple myeloma and new onset progressive renal failure with heavy and light-chain amyloidosis, cast nephropathy and proximal tubulopathy on renal biopsy.

Item Type: Article
Uncontrolled Keywords: AHL amyloidosis; Chemotherapy; Multiple myeloma; Proximal tubulopathy
Subjects: Medicine > KMC Manipal > Nephrology
Depositing User: KMC Library
Date Deposited: 09 Dec 2016 12:15
Last Modified: 09 Dec 2016 12:15

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