Removal rates of antibiotics in four sewage treatment plants in South India

Prabhasankar, P and Joshua, Derrick Ian and Balakrishna, K and Siddiqui, Iyanee Faroza and Taniyasu, Sachi and Yamashita, Nobuyosh and Kannan, Kurunthachalam and Akiba, Masato and Praveenkumarreddy, Yerabham and Guruge, Keerthi S (2016) Removal rates of antibiotics in four sewage treatment plants in South India. Environmental Science and Pollution Research, 23 (1). pp. 8679-8685. ISSN 0944-1344

[img] PDF
1616.pdf - Published Version
Restricted to Registered users only

Download (884kB) | Request a copy
Official URL:


The occurrence and removal of seven selected pharmaceutical compounds (PCs) in sewage treatment plants (STPs) in South India were investigated. The PCs selected for this study were sulfamethoxazole (SMX), trimethoprim (TMP), chloramphenicol (CAP), erythromycin (ERY), naproxen (NPX), bezafibrate (BZF), and ampicillin (AMP). Wastewater samples were collected from inlet and outlet of the STPs during pre-monsoon, monsoon, and post-monsoon seasons to investigate the seasonal influences in occurrence and removal rates. The analytical method was based on simultaneous extraction of all target compounds by solid phase extraction (SPE), using a hydrophilic–lipophilic-balanced (HLB) sorbent followed by high performance liquid chromatography tandem mass spectrometry (HPLC-MS/MS). The STP that catered exclusively to domestic wastewater had lesser concentrations of PCs compared to the STPs serving the combined hospital and domestic effluents.SMX was the dominant compound in all effluents with the highest concentration at 3.2 μg/L in the outlet of an STP. TMP and ERY were the other PCs present at higher concentrations in STP outlets (1 μg/L and 0–0.13 μg/L, respectively). Removal rates varied from 100 % for BZF to 60–100 % for SMX, CTX, and AMP.

Item Type: Article
Uncontrolled Keywords: Hospital effluents . Pharmaceutical compounds . India . Solid phase extraction . STP . Seasonal variations
Subjects: Engineering > MIT Manipal > Civil Engineering
Depositing User: MIT Library
Date Deposited: 15 Dec 2016 15:13
Last Modified: 15 Dec 2016 15:13

Actions (login required)

View Item View Item