Statin induced rhabdomyolysis with non oliguric renal failure: a rare presentation

Kareem, Hashir and Sahu, Devavrata and Rao, Sudhakar M and Devasia, Tom (2017) Statin induced rhabdomyolysis with non oliguric renal failure: a rare presentation. Journal of Clinical and Diagnostic Research, 11 (3). FD01-FD02. ISSN 0973-709X

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Statins are safe, well tolerated, efficient and time tested drugs for the management of hypercholesterolemia, and thus play a cardinal role in the management of patients with heart disease. Although safe in clinical practice, they are associated with adverse effects, clinically the most important and most severe being muscle related complications/myotoxicity. Rhabdomyolysis, though rare, is the most severe form of myotoxicity. The US Food and Drug Administration (USFDA) adverse event reporting system reports rate of statin induced rhabdomyolysis at 0.3-13.5 cases per 1,000,000 patients. We present a case of a 74-year-old male who presented with an acute coronary syndrome and was initiated on atorvastatin. However, patient developed atorvastatin induced rhabdomyolysis, with non oliguric renal failure, which subsequently improved on cessation of medication.

Item Type: Article
Uncontrolled Keywords: Atorvastatin; Hypercholesterolemia; Myotoxicity.
Subjects: Medicine > KMC Manipal > Cardiology
Depositing User: KMC Library
Date Deposited: 15 Jan 2018 06:05
Last Modified: 15 Jan 2018 06:05

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