Auditory P300 Event‑related potential: Normative data in the Indian Population

Praharaj, Samir Kumar (2018) Auditory P300 Event‑related potential: Normative data in the Indian Population. Neurology India, 66 (1). pp. 176-180. ISSN 0028-3886

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Abstract

Objective: To generate the normative data of auditory P300 event‑related potential for various age groups in the Indian population.Materials and Methods: Auditory P300 event‑related potentials, using the oddball paradigm, of healthy control participants in studies carried out at our institute were included to generate normative data in the age range of 10–50 years. The amplitude and latency of P300 for Fz, Cz, and Pz were selected for analysis.Results: For P300 amplitude, overall multivariate analysis of variance (MANOVA) was significant [Pillai’s Trace F (9/453) = 3.46, P < 0.001]. Follow‑up ANOVA showed significant difference across age groups at Fz,Cz, and Pz. For P300 latency, there was a trend towards significance for overall MANOVA [Pillai’s Trace F (9/453) = 1.68, P = 0.09]. Follow‑up ANOVA showed a trend towards significant difference across age groups at Fz only.Conclusion: Our study generated a P300 amplitude and frequency normative database at Fz, Cz, and Pz, which will serve as a reference for future studies attempting to define P300 abnormalities in various psychiatric disorders in Indian population.

Item Type: Article
Uncontrolled Keywords: Auditory; Event‑related potential; Oddball paradigm; P300; Normative
Subjects: Medicine > KMC Manipal > Psychiatry
Depositing User: KMC Library
Date Deposited: 17 Jan 2018 03:48
Last Modified: 17 Jan 2018 03:48
URI: http://eprints.manipal.edu/id/eprint/147871

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