Diabetic Cardiomyopathy: Tissue Doppler Imaging a Novel Insight

Rao, Karthik N and Ballala, Kirthinath and Samanth, Jyothi and Shetty, Ranjan and Vidyasagar, Sudha and Nayak, Krishnananda and Maiya, Arun G and Kumar, Sashi and Nandhini, Usha (2016) Diabetic Cardiomyopathy: Tissue Doppler Imaging a Novel Insight. Research Journal of Pharmaceutical, Biological and Chemical Sciences, 7 (1). pp. 1535-1540. ISSN 0975-8585

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Patients with diabetes mellitus (DM) are prone to develop heart failure even in the absence of evident hypertension and coronary artery disease. This entity is difficult to detect in early stages by conventional echocardiographic techniques. 32 asymptomatic TMT (tread mill stress test) negative DM patients compared with control subjects were screened and performed LV (left ventricle) strain, strain rate and tissue Doppler imaging. Tissue Doppler imaging revealed increased E/E’ of IVS (Inter ventricular septum) (p value<0.001) among DM suggestive of diastolic dysfunction. The tissue velocities E’ of both the LV lateral wall (p value=0.004) and RV (right ventricle) (p value =0.003) were reduced among DM. Similarly, the peak systolic strain (p value<0.001), and strain rate (p value<0.001) were significantly reduced among diabetic subjects. DM is an independent risk factor for myocardial dysfunction even in asymptomatic normotensive subjects. The changes that occur in the myocardium due to diabetic cardiomyopathy can be detected early, as the novel tissue Doppler is a noninvasive technique for early detection of Diabetic cardiomyopathy.

Item Type: Article
Uncontrolled Keywords: Diabetes mellitus; cardiomyopathy; Tissue Doppler; Strain rate
Subjects: Allied Health > MCOAHS Manipal > Cardiology
Allied Health > MCOAHS Manipal > Physiotherapy
Medicine > KMC Manipal > Cardiology
Medicine > KMC Manipal > Community Medicine
Medicine > KMC Manipal > Medicine
Depositing User: KMC Library
Date Deposited: 24 Jan 2017 08:46
Last Modified: 24 Jan 2017 08:46
URI: http://eprints.manipal.edu/id/eprint/148179

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